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KMID : 1145520160020010037
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Journal of Radiopharmaceuticals and Molecular Probes
2016 Volume.2 No. 1 p.37 ~ p.42
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A novel tricyclic derivative for PET imaging of the translocator protein
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Kwon Young-Do
Kim Hee-Kwon
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Abstract
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The translocator protein (TSPO) has attracted scientist's attention for Positron Emission Tomography (PET) imaging due to correlation with brain cancer, stroke, and neurodegeneration. Recently, GE-180, a novel tricyclic derivative has been developed as a new high affinity agent for the TSPO and evaluated to confirm a possibility for the TSPO ligand. In this highlight review, several studies for the novel TSPO radiotracer are described.
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KEYWORD
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GE-180, Positron emission tomography (PET), Translocator protein, PET radiotracer
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